'Optical Sorting' by Zipeng Zhang: Innovation in Biological Cell Sorting

Optical Sorting

Biological Cell Sorting for Zipeng Zhang

Efficiently screening and analyzing antibody discovery is crucial for reducing time and costs in antibody drug development. Traditional hybridoma technology faces challenges like long cycles, limited diversity, and inadequate functional analysis, hindering progress. The AI nanobiochip technology in the Light Workbench can rapidly separate, analyze, culture, and export tens of thousands of single cells simultaneously, completing positive plasma cell screening in one day.

Zipeng Zhang 2025 Collaboration Golden Press Kit № 166755

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Optical Sorting by Zipeng Zhang

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Biological Cell Sorting by Zipeng Zhang

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Zipeng Zhang Optical Sorting

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Zipeng Zhang Biological Cell Sorting

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Unique Properties

Efficiently screening and analyzing antibody discovery is crucial for reducing time and costs in antibody drug development. Traditional hybridoma technology faces challenges like long cycles, limited diversity, and inadequate functional analysis, hindering progress. The AI nanobiochip technology in the Light Workbench can rapidly separate, analyze, culture, and export tens of thousands of single cells simultaneously, completing positive plasma cell screening in one day.

Production Technology

Such products may utilize a variety of production technologies, including optical-induced dielectrophoresis, microfluidics, micro-nano fabrication, laser technology, imaging and detection, as well as automation and control. These technologies work in concert to achieve precise manipulation, efficient sorting, rapid analysis, and automated processing of cells, thereby providing powerful tools for biomedical research.

Project Duration

The project started in December 2020 in Beijing and finished in August 2023 in Beijing.

Operation Flow

First, the cells or other biological samples to be sorted are prepared and loaded into the microfluidic chip of the system. Then, the optical-induced dielectrophoresis technology is used to manipulate and sort the cells based on their properties. During this process, the imaging system captures the images of the cells, and the software analyzes the images in real-time to identify and classify the cells. Finally, the sorted cells are collected, and the results are output and processed for subsequent research.

Research

In our research, we looked into a particular topic to gain more insights. We conducted experiments or studies, using various tools like scientific instruments or software, depending on what we were focusing on. If it involved people, we had participants; if it was about animals or cells, those were our subjects. Through our methods, we observed, collected data, and tested different conditions. The results revealed interesting findings, such as a new relationship or a significant change. These findings gave us new understandings and could point the way for future research.

Inspiration

The Optical Cell Sorting System is a breakthrough in cell sorting for biomedical research. It replaces time-consuming, sample-damaging manual sorting with optoelectronic dielectrophoresis, which precisely controls cells for efficient, undamaged sorting. This technology boosts accuracy and speed, providing a reliable, streamlined cell sorting and culture process. The Light Operator enhances lab efficiency, enabling scientists to advance cell research.

Project Overview

Optical Sorting Biological Cell Sorting has been a Golden winner in the Scientific Instruments and Research Equipment Design award category in the year 2024 organized by the prestigious A' Design Award & Competition. The Gold A' Design Award is granted to designs that demonstrate a high level of innovation and a significant impact on their intended audience. Recognized as a major achievement by the A' Design Awards, these designs are characterized by their visionary approach and the exceptional skill of their creators. Winners of the Gold A' Design Award are noted for their ability to push the envelope in art, science, design, and technology, delivering solutions that not only meet but exceed expectations. These designs serve as benchmarks for excellence, encouraging further innovation and inspiring future generations of designers.

Image Credits

For design images and photos please credit Zipeng Zhang.

Golden Recognition

Zipeng Zhang was recognized with the coveted Golden A' Design Award in 2025, a testament to excellence of their work Optical Sorting Biological Cell Sorting.

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